4′-Methylpropiophenone CAS 5337-93-9

Molecular Weight: 148.2
Molecular Formula: C10H12O
Appearance: Light yellow liquid
Purity: ≥95%
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4′-Methylpropiophenone CAS 5337-93-9 CAS 5337-93-9 is a chemical compound containing an aromatic ketone, specifically propiophenone with a methyl group located at C-4. It is a clear light yellow liquid, soluble in chloroform and hexane.

4′-Methylpropiophenone CAS 5337-93-9



Cas No.







Ethyl 4-Methylphenyl Ketone;


Molecular weight

148.2 g/mol


0.993 g/mL at 25 °C(lit.)

Melting Point

7.2 °C

Boiling point

238-239 °C(lit.)


Soluble in chloroform and hexane


Light yellow liquid



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4′-Methylpropiophenone CAS 5337-93-9 Storage Conditions

  1. Store in a cool place to prevent excessive heat exposure.
  2. Keep the container tightly closed to prevent air or moisture from entering.
  3. Store in a dry and well-ventilated place to maintain stability.

4′-Methylpropiophenone uses

Some of the common applications of 4′-Methylpropiophenone are as follows:
1. 4′-Methylpropiophenone is commonly used as an intermediate in drug synthesis. It is used to synthesise more complex compounds.
2. 4′-Methylpropiophenone is used in the fragrance and flavour industry due to its aromatic nature of its odour. It is often used to create unique aromas and flavours in products such as perfumes, colognes, soaps and food additives.
3. researchers and chemists use 4′-methylpropiophenone as a starting material for developing new compounds.
4. 4′-Methylpropiophenone can participate in a wide range of organic synthesis reactions. Through further chemical transformations, it can be used to produce other ketones, alcohols and carboxylic acids.
5. In a laboratory setting, 4′-methylpropiophenone can be used for analytical purposes or as a reference compound.

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4 methylpropiophenone synthesis

To synthesize 4-methylpropiophenone, mix acetophenone and isobutyraldehyde in a 1:1 ratio with an acid catalyst. Add a solvent and heat the mixture under reflux conditions for 4-6 hours. After cooling, extract the crude product with water, separate the organic layer, and dry it with drying agents. Optionally, purify the product through simple distillation.



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