Technical Data
Melting point | 187-189°C |
storage temp. | 2-8°C |
solubility | DMSO: >20mg/mL |
form | white powder |
color | White |
Water Solubility | 3.488g/L(temperature not stated) |
Merck | 14,8489 |
BCS Class | 1 |
Stability: | Store in Freezer |
InChIKey | DEIYFTQMQPDXOT-UHFFFAOYSA-N |
SMILES | C1(=CC(=CC=C1OCC)S(=O)(=O)N1CCN(C)CC1)C1=NC(C2N(N=C(CCC)C=2N1)C)=O.C(O)(C(=O)O)(CC(=O)O)CC(=O)O |
CAS DataBase Reference | 171599-83-0(CAS DataBase Reference) |
Biological Activity
Sildenafil citrate is an orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro. Sildenafil citrate promotes mobilization of hematopoietic stem cells (HSCs) in combination with AMD 3100 (Cat. No. 3299). Reduces pulmonary pressure and edema.
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